Psilocybin Mushrooms, Ketamine & DMT

The Center for Medicinal Mindfulness has been working professionally with Psychedelic Cannabis since 2014, with Ketamine since 2019, and in November of 2022, Colorado voters legalized the personal use of dimethyltryptamine, ibogaine, mescaline (excluding peyote), psilocybin, and psilocin (aka natural medicines). While sale of natural medicine is still restricted, persons twenty-one years of age or older can now legally ingest and use natural medicines in Colorado for personal use.

Medicinal Mindfulness celebrates this historic moment in psychedelic history by offering support services to those engaged in personal use of natural medicines in addition to our psychedelic cannabis and ketamine services. We are able to provide services with psilocybin mushrooms and DMT through our study of the new personal use support service regulations and as a religious non-profit. 

Medicinal Mindfulness’ personal use services include bona fide harm reduction, therapy, and support services.  Medicinal Mindfulness also offers beneficial community-based use and healing services to those individuals interested in using natural medicines in a group or community setting.

Below is a brief description of our work with Ketamine, Psilocybin Mushrooms and DMT.


Ketamine is a safe, legal, and highly effective prescription psychedelic medicine being used to treat depression, trauma, anxiety and addiction. It is a dissociative anesthetic commonly used in surgeries and hospitals worldwide and has been safely administered on humans for decades. Dissociation is a sense of disconnection from one’s ordinary reality and sense of self.

At the Center for Medicinal Mindfulness, we use a sub-anesthetic dose to induce a non-ordinary state of consciousness (NOSC) which leads to psychedelic and euphoric effects. Ketamine is proving successful in providing symptom relief for depression, traumatic stress, anxiety, and other mental health conditions when administered in conjunction with professional support and guidance.

Ketamine-Assisted Psychedelic Therapy

Ketamine-Assisted Psychedelic Therapy (KAPT) is a modality that combines the professional oversight of a medical doctor, the emotional support from a trained therapist or guide using MBPT with the medicinal effects of ketamine. Ketamine serves as a catalyst to bring forward therapeutic content within a non-ordinary state of consciousness while the therapist or guide is present to support clients with deepening and integrating these experiences.

These sessions provide a full body and soul holistic psychedelic experience with the clinical and medical oversight required to work with this medicine safely and effectively. Sessions combine trauma-informed and evidence-based practices with mindfulness practices, ceremony, ritual, and somatic therapies, within a spiritual orientation and energetic/transpersonal paradigm (if requested). A standard session is scheduled for 3 hours, creating space for a deep journey and gentle landing. Many other ketamine clinics offer only 60-90 minute sessions. In typical medical ketamine clinics and private practice settings, clients are offered only low-dose (psycholytic) sessions instead of psychedelic ketamine sessions, and are not provided with the psychological support needed to get the most benefit out of ketamine therapy. Our center is committed to maintaining best practices in KAPT and, because of that commitment to the healing and wellbeing of our clients, our approach offers much more than the medical-only trend.

Medicinal Mindfulness Foundation Psilocybin Mushroom & DMT Support Services

Psilocybin and psilocin are hallucinogenic alkaloids found in nearly 200 strains of mushrooms that grow on every continent.  The body converts psilocybin into psilocin, which is the main psychoactive compound. There is significant evidence to suggest that this compound has been used for ritual, medicinally, and recreationally for at least 12,000 years.  We can find depictions of mushroom use on murals in Australia that archeologists have dated to 10,000 BCE and in Spain in 4,000 BCE.  There is a history of their ceremonial use in Central America by the Aztec and Mayans, in Siberia, in ancient Greece, ancient Egypt and across Europe. Since their popularization in the 1950s in Western culture they were nicknamed “magic mushrooms” and they can be found wild and cultivated all over the world.  Psilocybin and psilocin have been thoroughly studied for their potential benefits to mental health by reputable universities such as Harvard, Stanford, Cambridge and are actively being studied at John Hopkins University.

N,N-DMT is a naturally occurring psychedelic medicine found in hundreds of plant and animal species. It is most commonly known as an active ingredient in the psychedelic brew, Ayahuasca, but can also be taken in a smokable form called “changa” and is commonly derived from Mimosa Hostilis root bark. DMT is a very potent and very fast acting psychedelic medicine most notably studied by Rick Strassman and popularized in his book DMT: The Spirit Molecule. The effects are most notable for transporting psychonauts into other worlds and dimensions that are inhabited by other dimensional beings that feel “more real than real.”

The Natural Medicine Support Services taught by Psychedelic Sitters School are designed to be compliant with the Colorado Natural Medicine Health Act and subsequent legislation. We provide proper dosing instructions, informed consent documentation, and safe and sacred guiding protocols that support the personal use of these medicines. 

Additional Requirements for Natural Medicine and Ketamine Experiences

The Student Handbook provides all of the necessary documentation to work with us using Psychedelic Cannabis and Breathwork and prepares you for the foundational courses in Psychedelic Sitters School. Working and training with Ketamine requires becoming a client of the Center for Medicinal Mindfulness, additional clinical paperwork, and informed consent documents. Ketamine requires a prescription from a medical provider. Working and training with Psilocybin Mushrooms or DMT also require a medical safety review and additional informed consent documents that are not provided in the Student Handbook. There are additional medical contraindications, including some prescription medications, that may limit or postpone participating in trainings with these psychedelic medicines.